Dr. Singhal is originally from San Mateo and she received her undergraduate degree in Biophysics at Johns Hopkins University. She then attended the Albert Einstein College of Medicine in New York where she completed her M.D. program while also receiving a Ph.D. in Molecular Pharmacology. She completed her Surgical Residency at the University of Washington in Seattle in one of the nation’s top surgical training programs. When Dr. Singhal was completing her residency, she decided to complement her understanding of molecular pharmacology of cancer medications with a clinical specialty in surgical oncology. She went on to complete a fellowship in Surgical Oncology at the City of Hope National Cancer Center, a leader in Minimally Invasive Surgical Oncology (MISO). Her research there focused on discovering the interactions of chemotherapy and a wide spectrum of natural agents, and the impact on liver function.
Dr. Singhal has extensive training in the cellular and molecular mechanisms in the development of malignancy. Clinically, she has a multidisciplinary approach- considering Chemotherapy, Radiation and Surgery. It provides Dr. Singhal a comprehensive view of cancer and a better opportunity to treat the disease. In 2005, she became the Medical Director for the Cancer Program at El Camino Hospital. With her leadership, the program has expanded from 200 new patients a year to over 700 new patients per year, and has received certification from the Commission on Cancer with 6 commendations in 2013 and 2016. More recently, she has been involved in medical device start ups and digital health. She serves as the Chief Medical Officer for Cyrcadia Health the manufacturer of the Smart Bra. She is the Primary Investigator for several clinical trials, including a BioBank with the Canary Center at Stanford.
Appointments: · ACS Board of Directors, SCC Region · Susan G. Komen Foundation LA Chapter, Co-chair Education Committee 2003-05
Professional & Academic Societies: · Society of Surgical Oncology · American College of Surgeons, Fellow · American Society of Clinical Oncologists · Alpha Omega Alpha(MD honor society) · Harkins Society-University of Washington
R&D Chemist, Applied Biosystems, Foster City, CA; DNA Sequencing R&D. Developed DNA standards for 1st DNA sequencer. 1986, 1987-1988, 1990
Research Technician II, HHMI, Stanford University, CA. 1988-1989
Research Intern, Johns Hopkins University, Dr. Robert J. Maier Lab. 1985-1987
Selected Publications: Mallick, S. and Horwitz, S.B.. Transcriptional regulation of the murine multidrug resistance gene, mdr1b, by progesterone occurs via an indirect mechanism. DNA Cell Biol: 16(7) 807-818. 1997
Mallick, S. and Horwitz, S.B.. "A Role for Progesterone in Multidrug Resistance" in Estrogens and Progestins and their Antagonists in Health and Disease. Volume 2. pp123--151. 1996
Kuo, D., Mallick, S., Shen, H-J., DeVictoria, C., Jones, J., Fields, A., Goldberg, G., Runowicz, C., and Susan Band Horwitz. Quantitative analysis of multidrug resistance gene (MDR1) expression in endometrial cancer and benign endometrium using the method of reverse transcription polymerase chain reaction (RT-PCR) Clinical Cancer 2:1981-1992. 1996
Heiner, C., Mallick, S., Wan, A., Hunkapillar, M.. Taq polymerase: Increased versatility in DNA Sequencing. Applied Biosystems, User Bulletin #10, 1988
Stults, L., Mallick, S., and Maier, R. J.. Nickel uptake in B. japonicum. J. Bacteriol. (1987) 169: 1398-1402
Presentations: Mallick, Shyamali. Activation of Hepatic Clearance mechanisms by herbal agents. COH Symposium March 2003
Mallick, S., Canty, T. and Meissner, M.. Mesenteric venous ischemia as a result of hypercoagulable states. Pacific Vascular Society Mtg. Couer D’Alene, ID. 2000
Mallick, S., Canty, T. and Meissner, M.. Hypercoagulable states as a cause of mesenteric ischemia. ACS- Washington State Chapter Mtg. Lake Chelan WA. 2000
Mallick, Shyamali. Mesenteric Venous Thrombosis resulting from Hypercoagulable states: Three Case Reports and Review of the Literature. GI Grand Rounds March 2000
Mallick, Shyamali. DIC in the multiple trauma patient. Trauma Conference February 2000
Mallick, Shyamali. Traumatic iliac arterial injuries. Trauma Conference November 2001
Mallick, Shyamali. Transmediastinal gunshot wounds. Trauma Conference March 2002
Dr. Shyamali Singhal - General Surgery and Advanced Surgery. Specializing in Surgical Oncology for the treatment of Cancer - Melanoma (Skin Cancer), Colon Cancer, Stomach Cancer, Liver Cancer, Pancreatic Cancer, Breast Cancer, etc. Experienced Whipple Procedure Surgeon. Serving Silicon Valley - Mountain View, Los Altos, Palo Alto, Sunnyvale, Santa Clara, Saratoga, Cupertino, San Jose, Campbell and the San Francisco Bay Area - Menlo Park, East Palo Alto, Redwood City, Belmont, San Mateo, Burlingame, Millbrae, Daly City, San Francisco, South San Francisco
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